How many replication origins would you need to complete DNA replication if the replication fork can move at 75 nucleotides per second?

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  • 5 months ago

    Each replication origin forms 2 replication forks, one in each direction from the origin. So, each origin leads to 150 nucleotides / second

    8 hr X 3600 seconds/hr = 28800 seconds

    6,000,000,000 nucleotides / 28800 s = 208333 nucleotides / second must be synthesized

    208333 nucleotides/s / 150 nucleotides/s / origin = 1389 origins or about 1400 origins

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