Help in english?
can you please explain to me the results using simple words? Thank you
Results: After 12 months, the response rate (intention-to-treat/last-observation-carried-forward approach) did not differ between pumpkin seed extract and placebo. In the case of pumpkin seed (responders: 58.5%), the difference compared with placebo (responders: 47.3%) was descriptively significant. The study products were well tolerated.
- Mr. SmartypantsLv 72 months agoFavourite answer
I'm afraid it might take a lot more 'simple' words. 8^)
So we have a study here in which some people are given pumpkin seed extract and some are given a pill which does nothing at all (that's what a placebo is). Nobody really knows what they're getting. The idea is to see if the people who got the real pumpkin seed extract are getting whatever effect the pumpkin seed stuff was supposed to have. This went on for 12 months before they gathered the results and did the math to see how it worked.
Whenever you do a study like this, some results are missing. Someone who was supposed to take their blood pressure every day, for instance, will skip some days. One way to deal with this is just to use the previous day's number to fill in the missing day. That's called 'last result carried forward'. 'Intention to treat' is another way of supplying missing data.
What they found was that after 12 months, the group that got the pumpkin seed extract and the group that got the placebo did about equally as well. This would suggest that the pumpkin seed extract is not effective.