Even if a gene is altered with a mutation, it may end up making precisely the same protein as before…” How is that possible?

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  • Cowboy
    Lv 6
    4 weeks ago

    Silent mutations don't change tertiary structure...but most others do, even though a protein's active center may remain.

  • 4 weeks ago

    ..

    The genetic code is "degenerate" -- more than one codon can specify a particular amino acid.

    Your mutation just happened to change a codon to another codon that codes for the same amino acid (or from one STOP codon to one of the other STOP codons).

    OR

    Your mutation occurred in a non-coding part of the gene, and did not change the noncoding functionality. e.g. your mutation changed the sequence within an intron, but it's still an intron so the protein product is unchanged.

  • CRR
    Lv 7
    4 weeks ago

    There is some redundancy in the genetic code so amino acids can be encoded by more than one codon. Some mutations will change the codon to another that produces the same amino acid.

    However the "synonymous" codons can have slightly different effects, such as producing a pause that helps protein folding, so it can still affect the results.

  • One explanation is that the mutated section of the DNA has no effect on the protein we're focused on

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  • Henry
    Lv 4
    4 weeks ago

    Genes don't make proteins, the protein chamber organelle thing does.

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