I am working on my car, I am wishing to lower the transmission but I am not sure if I need to lower the subframe as well.?

I am working on my Nissan Sentra 2016, I am wishing to lower the transmission but I am not sure if I need to lower the subframe as well before I lower the transmission. I tried looking for info on the internet but found nothing useful. if someone could help me out with this that would be great. Thank you.
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