What is the best way for me to get to/from my hotel in NYC?

My flight will land around 10 a.m on a Sunday, so would it be easier to take a taxi, uber, or the bus/subway? It will only be my mom and I plus two carry-ons. We will be purchasing metro cards for the time we are there. Also, that Saturday, our flight leaves around 7 a.m so which option would be best at that time?... show more My flight will land around 10 a.m on a Sunday, so would it be easier to take a taxi, uber, or the bus/subway? It will only be my mom and I plus two carry-ons. We will be purchasing metro cards for the time we are there. Also, that Saturday, our flight leaves around 7 a.m so which option would be best at that time? We re flying to and from LaGuardia.
Update: Hotel is a few streets above Madison Square Garden. Sorry I forgot to include that!
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