The obvious "Fors" are, "cleanliness" during generation, relative reliability and National Control.
Against are the issues of waste disposal, toxicity of fissile materials, expense and security.
Of these, expense is the greatest problem. Back in 1993, when the initial contracts were handed out for the decommissioning of current nuclear facilities, the company for which I worked, was looking a in excess of £30billion worth of business. That has now stretched to well over £100billion.
Security will always be an issue, but has not yet caused a real problem. There are now reactor designs, which are relatively cheap and do not produce fissile waste.
There is still the issue of what to do with the highly radioactive waste. At some time there is going to be an unavoidable log jam in waste containment resources, which is bound to precipitate other security problems.
Unfortunately the increasing propensity of OPEC and related Oil Producing Countries to use their resources as a political weapon, is leaving us with little choice. "Renewables" will never give us enough energy, so we are basically bound to tread the Nuclear Path.
However, there may be an alternative: Laser Furnaces.
Raising the temperature of water to temperatures of around 2000deg. causes the water to explosively decompose. In a purely aqeous environment, the reduction in temperature of the resultant plasma causes another explosive reconstitution into water, in the form of super-heated steam. There has to be a level of scale, in which such a clean, non nuclear process produces an energy surplus, which permits industrial levels of energy production.
